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Two defense-related genes, encoding a GST and a cytochrome P450, were regulated downstream of WRKY45, but were not regulated by NH1, suggesting independence of the WRKY45 and NH1 pathways (Shimono et al., 2007)

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Abbreviations : PH Pulmonary hypertension, MI Myocardial Infarction, GPX4 Glutathione Peroxidase 4, SLC7A11 Solute Carrier Family 7 Member 11, NRF2 Nuclear factor erythroid2-related factor 2, AMPK AMP-activated protein kinase, SIRT1 Sirtuin 1, GSH Glutathione, FXN Iron-sulfur cluster biogenesis protein Frataxin, ROS Reactive oxygen species, HO-1 Heme oxygenase-1, GSK3β Glycogen synthase kinase-3, AKT Protein kinase Myocardial infarction MI culminates in cardiac detriment precipitated by cellular death and inadequate self-regeneration of cardiomyocytes [596]