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DOI: 10.1111/acel.12102 Campbell MD et al

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Furthermore, it has been demonstrated that psychostimulants and the alpha2-adrenoreceptor agonist guanfacine can occasionally reduce hyperactivity, impulsivity, and inattention in SHR, which lends some support to the model's predictive validity (Myers et al.,1982, Sagvolden,2006)