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Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)

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Conditioned media derived from sB-treated keratinocytes inhibited HUVEC tube formation We performed a tube formation assay to determine whether angiogenesis-related factors released from CAV-1-downregulated epidermis promote angiogenesis (Fig