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Tat, with or without methamphetamine, increases microtubule associated protein 1 light chain 3-II (LC3-II), Beclin-1, and the autophagy-related proteins ATG5 and ATG7

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In addition, accessory proteins such as COQ4, COQ8A/B, COQ9 and COQ10A/B are believed to facilitate enzyme complex assembly, substrate channeling or stabilization of the biosynthetic complex (commonly referred to as the ‘CoQ synthome’) but their precise molecular functions are still under investigation

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