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Patients Caucasian overweight (BMI 25–29.9 kg m −2 ), outpatients, males and females, aged 40–65 years, with never-treated stage 1 hypertension (systolic BP (SBP) ⩾140 and 3 kg within the previous 3 months, diabetes mellitus, secondary hypertension, myocardial infarction or stroke in the preceding 6 months, unstable angina, congestive heart failure, significant thyroid, pulmonary, renal or hepatic disease, gastrointestinal disorders, pregnancy or nursing, significant neurological or psychiatric disturbances (including alcohol or drug abuse) or use of anorexiant agents, laxatives, cyproheptadine, antidepressants, antiserotoninergics, phenothiazines, barbiturates, oral corticosteroids, antipsychotics or hormone replacement therapies

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Vitamin C, B5, and B6 support the reduction of tiredness and fatigue, while chromium helps maintain balanced metabolic function

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