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Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): A multicentre, open-label, randomised phase 3 trial

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found increased oxytocin levels in depressed subjects, and more recently Tabak et al., examining the role of oxytocin in social anxiety in humans, reported increased plasma concentrations of oxytocin following the Trier Social Stress Test (TSST), but this increase was specific to women, and that social anxiety moderated the OXT increase with more socially anxious participants showing greater increases than those with lower levels of social anxiety [57]