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In a study by Sola et al ., intervention with 150 mg of Irbesartan or 300 mg of ALA or both or placebo for 4 weeks decreased IL-6 in intervention groups.[23] In another study, 600 mg ALA supplementation for 8 weeks in hemodialysis patients significantly decreased hs-CRP level.[28] In addition, results of a review article showed that supplementation of ALA can reduce ischemia-reperfusion injuries in multiple organs (nervous system, heart, kidney, liver, intestine, gonad gland, retina, and limb).[5] Several studies have demonstrated the antioxidant and anti-inflammatory properties of ALA[1] and shown that ALA decreases the expression of vascular adhesion molecule-1, endothelial adhesion of human monocytes, and inhibits NF-κB.[29] NF-κB is a cytokine-mediating expression of several genes involved in inflammation and the migration of endothelial cells

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It's somewhat of a jack-of-all-trades stat-wise, but its best asset is its bulk, at 100 Defense and 105 Special Defense